Uniformed Services University of the Health Science F. Edward Hebert School of Medicine Graduate Programs in the Biomedical Sciences and Public Health

نویسندگان

  • F. EDWARD
  • Philip
  • Smith
چکیده

This work examines a newly developed dynamic air sampling technique, known as HighSurface Area Solid Phase Micro Extraction (HSA-SPME), in sampling and analysis of chemical warfare agent surrogate and degradation compounds. The polymer coating of this device has 10 times the surface area of commercially available SPME fibers, and at high sample flow rates (4 L·min) provided increased extraction efficiency in terms of mass per unit time. The high sensitivity with short sampling durations (5-60 seconds) can be beneficial for decision making and minimizing time in a field response scenario contaminated environment, when time is of the essence. Use of a tandem HSA-SPME method, in which two devices are joined in series to double the sample collection surface area (160 mm), permits low detection limits (<1 ppbv by GC/MS) with short sampling times (10-15 sec). The speed, sensitivity and ease-of-use are demonstrated in comparison with a laboratory accepted standard chemical pre-concentration module used for sample

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تاریخ انتشار 2011